Driving Question: What is Cancer?
Project: Create a video (script or animation) to represent the cell cycle, mitosis, and the formation of cancer.
Supplemental Questions:
1. What does family history have to do with cancer?
2. Why do some siblings look different while other siblings look similar?
3. How do humans become so complex?
1. What does family history have to do with cancer?
2. Why do some siblings look different while other siblings look similar?
3. How do humans become so complex?
Standards:
5. Students can use the full range of science and engineering practices to make sense of natural phenomena and solve problems that require understanding how individual organisms are configured and how these structures function to support life, growth, behavior and reproduction.
GLE 1: DNA codes for the complex hierarchical organization of systems that enable life's functions.
Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells.
GLE 2: Growth and division of cells in complex organisms occurs by mitosis, which differentiates specific cell types.
Use a model to illustrate the role of cellular division (mitosis) and differentiation in producing and maintaining complex organisms
GLE 1: DNA codes for the complex hierarchical organization of systems that enable life's functions.
Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells.
GLE 2: Growth and division of cells in complex organisms occurs by mitosis, which differentiates specific cell types.
Use a model to illustrate the role of cellular division (mitosis) and differentiation in producing and maintaining complex organisms
Assignments: |
Objectives: |
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1. Check Google Classroom for all graded "questions."
2. Group project role play with script (see below for requirements). 3. Cancer role play script reflection - posted on Google Classroom. 4. "How cells become specialized" reading and video. |
Upon completion of this lesson, students will be able to:
1. Identify common misconceptions about cancer 2. Create a graphic organizer to represent what they know about cancer 3. Summarize the characteristics of the cell cycle and its regulation 4. Recognize the consequences of uncontrolled cell division 5. Compare the appearance, structure, function, and replication of healthy cells to those of cancerous cells 6. Describe how cancer develops |
Vocabulary:
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Cell Structure:
Cell Membrane
Centriole Chromatid Chromosome Cytoplasm Nuclear envelope Nucleus Organelle Spindle fiber |
Genetics:
DNA
Gene Inheritance Mutation Nondisjunction Oncogene Proto-oncogene Replication Tumor suppressor gene |
Cell Cycle and Cancer:
Anaphase
Apoptosis Cancer Cell Checkpoint Cell Cycle G0 Phase G1 checkpoint G1 phase G2 phase G2 checkpoint S phase Tumor |
Mitosis:
Mitosis
Prophase Metaphase Anaphase Telophase Cytokinesis |
Cell Division Role Play Project:
Task: Choose to create either a skit, a comic strip, or a video animation.
Voiceover/Teacher
Narrator
Enzyme 1
Enzyme 2
Cell Membrane
Centrioles
DNA/Chromatids (Students must identify DNA or Chromatid depending on the step within the script.)
Mutated Chromatids/Mutated DNA 1 molecules
Nuclear Membrane/Envelope
Groups must be prepared to either perform the skit in class, show the video to the class, or demonstrate the comic strip.
Students presenting Normal Cell Division go first, followed by the groups presenting Tumor Suppressor Gene Mutation and Proto-oncogene Mutation.
Remember the purpose of the project! Each group must demonstrate that usually the cells in Tumor Suppressor Gene Mutation and Proto-oncogene Mutation would go through apoptosis. However, cancer cells avoid apoptosis and keep growing and dividing, resulting in a tumor.
- Groups will be assigned a script that demonstrates either Normal Cell Division, Tumor Suppressor Gene Mutation, or Proto-oncogene Mutation.
- A script will be provided to each group and must be followed precisely. There is a link below as well as on Google Classroom if you need another script.
- Groups are encouraged to create a story beyond the simple script.
Voiceover/Teacher
Narrator
Enzyme 1
Enzyme 2
Cell Membrane
Centrioles
DNA/Chromatids (Students must identify DNA or Chromatid depending on the step within the script.)
Mutated Chromatids/Mutated DNA 1 molecules
Nuclear Membrane/Envelope
Groups must be prepared to either perform the skit in class, show the video to the class, or demonstrate the comic strip.
Students presenting Normal Cell Division go first, followed by the groups presenting Tumor Suppressor Gene Mutation and Proto-oncogene Mutation.
Remember the purpose of the project! Each group must demonstrate that usually the cells in Tumor Suppressor Gene Mutation and Proto-oncogene Mutation would go through apoptosis. However, cancer cells avoid apoptosis and keep growing and dividing, resulting in a tumor.
| script_for_cancer.pdf |
Rubric:
